Salmon and shrimp lasagna rolls

Salmon and shrimp lasagna rolls is a medium Italian-American recipe that serves 4. 460 calories per serving. Recipe by Tiff Spice Be Rite! on YouTube.

Prep: 35 min | Cook: 20 min | Total: 1 hr 10 min

Cost: $91.93 total, $22.98 per serving

Ingredients

  • 0.5 lb Salmon Fillet (cut into small dice)
  • 0.5 lb Shrimp (peeled, deveined, finely chopped)
  • 0.5 lb Mahi‑Mahi Fillet (cut into small dice)
  • 2 bags Fresh Spinach (about 10 oz each, roughly 20 oz total, chopped fine after cooking)
  • 2 tsp Cajun Seasoning
  • 1 tsp Garlic Powder
  • 1/2 tsp Salt
  • 1/4 tsp Black Pepper (freshly ground)
  • 1 medium Onion (finely chopped)
  • 3 pieces Garlic Cloves (minced)
  • 2 tbsp Garlic Butter (softened, can use regular butter + minced garlic)
  • 1 tbsp All-Purpose Flour (for roux)
  • 1 cup Half‑and‑Half
  • 4 oz Cream Cheese (softened, cut into cubes)
  • 1/2 cup Cheddar Cheese (shredded)
  • 1/4 cup Parmesan Cheese (freshly grated)
  • 2 cups Mozzarella Cheese (shredded, plus extra for topping)
  • 8 sheets Lasagna Noodles (regular, not no‑boil)
  • 2 tbsp Fresh Parsley (chopped, for garnish)

Instructions

  1. Prepare the Seafood

    Dice the salmon, shrimp, and mahi‑mahi into small, uniform pieces. Set aside in a bowl.

    Time: PT5M

  2. Cook the Spinach

    In a large skillet over medium heat, add a splash of oil and the fresh spinach. Cook, stirring, until wilted, then transfer to a cutting board and chop finely.

    Time: PT5M

  3. Season the Seafood

    Return the diced seafood to the skillet, sprinkle with Cajun seasoning, garlic powder, salt, and pepper. Toss to coat and cook just until the shrimp turn pink, about 2‑3 minutes. Remove and set aside.

    Time: PT5M

  4. Sauté Onion & Garlic

    In the same skillet, add a little more butter if needed, then sauté the finely chopped onion until translucent (≈3 min). Add minced garlic and cook another 30 seconds.

    Time: PT4M

  5. Make the Roux

    Add the remaining garlic butter to the pan, melt, then stir in 1 tbsp flour. Cook, stirring constantly, for 1 minute to form a light roux.

    Time: PT2M

  6. Create the Creamy Sauce

    Gradually whisk in the half‑and‑half, adding a little at a time until smooth. Continue stirring until the sauce thickens, about 3‑4 minutes. Season with additional Cajun seasoning, salt, and pepper to taste.

    Time: PT5M

  7. Combine Cheese & Spinach

    Reduce heat to low. Add the cream cheese, letting it melt into the sauce. Stir in shredded cheddar, grated Parmesan, and the chopped cooked spinach until fully incorporated.

    Time: PT3M

  8. Boil Lasagna Noodles

    Bring a large pot of salted water to a boil. Add the lasagna sheets and cook until al dente (≈8‑9 min). Drain in a colander and lay flat on a clean kitchen towel.

    Time: PT10M

  9. Assemble the Rolls

    Place a generous spoonful of the spinach‑cheese mixture onto each noodle, then top with a few pieces of the seasoned seafood. Roll the noodle tightly, place seam‑side down in the prepared baking dish, and repeat for all noodles.

    Time: PT8M

  10. Add Sauce & Cheese Topping

    Pour any remaining sauce over the rolled noodles, ensuring each roll is well‑coated. Sprinkle the remaining shredded mozzarella evenly on top, then garnish with chopped parsley.

    Time: PT3M

  11. Bake

    Preheat the oven to 400°F. Bake the lasagna rolls for 10 minutes, then remove foil (if used) and bake an additional 5 minutes until the cheese is bubbly and lightly golden.

    Time: PT15M

    Temperature: 400°F

  12. Rest & Serve

    Allow the dish to rest for 5 minutes before serving so the rolls hold their shape.

    Time: PT5M

Nutrition Facts

Calories
460
Protein
32 g
Carbohydrates
38 g
Fat
22 g
Fiber
4 g

Dietary info: Pescatarian, Contains dairy, Contains gluten

Allergens: Dairy, Gluten, Shellfish, Fish

Last updated: April 6, 2026

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Salmon and shrimp lasagna rolls

Recipe by Tiff Spice Be Rite!

A creative twist on classic lasagna: tender lasagna noodles rolled with a flavorful mixture of salmon, shrimp, mahi‑mahi, spinach, and three cheeses, baked in a creamy Cajun‑seasoned sauce. Perfect for a comforting dinner that feels both elegant and home‑cooked.

MediumItalian-AmericanServes 4

Shop all ingredients on Amazon in one click • Printable PDF with shopping checklist

Source Video
26m
Prep
44m
Cook
10m
Cleanup
1h 20m
Total

Cost Breakdown

$91.93
Total cost
$22.98
Per serving

Critical Success Points

  • Cooking the spinach just until wilted and chopping it fine.
  • Forming a smooth roux and gradually adding half‑and‑half to avoid lumps.
  • Ensuring the sauce is thick but pourable before mixing cheese.
  • Rolling the lasagna noodles tightly without tearing.
  • Baking at 400°F for the exact time to melt cheese without over‑browning.

Safety Warnings

  • Handle raw seafood with clean hands and sanitize all surfaces after use.
  • Hot oil and butter can splatter; use a splatter guard if needed.
  • Use oven mitts when removing the hot baking dish.

Frequently Asked Questions

Everything you need to know about this recipe

Q

What is the cultural significance and history of seafood lasagna rolls in Italian‑American cuisine?

A

Seafood lasagna rolls are a modern American adaptation of traditional Italian lasagna, blending the classic layered pasta concept with coastal ingredients popular in the United States. While not a historic Italian dish, it reflects the Italian‑American tradition of incorporating locally abundant seafood into familiar comfort foods.

cultural
Q

What are the traditional regional variations of lasagna in Italy that inspired this seafood version?

A

In Italy, lasagna varies by region—Northern versions often use béchamel and meat, while Southern versions feature tomato‑based sauces and ricotta. The seafood twist mirrors coastal Italian dishes like lasagne al mare from Liguria, which incorporate shrimp, clams, and fish into pasta layers.

cultural
Q

How is seafood lasagna rolls traditionally served in Italian‑American households?

A

It is typically served as a main course for dinner, accompanied by a simple green salad, crusty bread, and a glass of white wine. The rolls are presented on a platter, garnished with fresh parsley or basil for color.

cultural
Q

What occasions or celebrations is seafood lasagna rolls associated with in American culture?

A

Because it combines elegance with ease, the dish is popular for family gatherings, holiday meals, and casual dinner parties where a hearty, yet refined, casserole is desired.

cultural
Q

What authentic ingredients are essential for an authentic Italian‑American seafood lasagna roll, and what are acceptable substitutes?

A

Key ingredients include fresh seafood (salmon, shrimp, mahi‑mahi), spinach, mozzarella, Parmesan, and a creamy béchamel‑style sauce. Substitutes can include other firm white fish, frozen spinach (thawed and drained), or a blend of cheddar for a sharper flavor.

cultural
Q

What are the most common mistakes to avoid when making seafood lasagna rolls at home?

A

Common errors include over‑cooking the seafood, using over‑soft noodles that break, and adding the flour too quickly which creates lumps in the sauce. Follow the timing cues and whisk the sauce gradually to prevent these issues.

technical
Q

Why does this recipe use a roux with butter and flour instead of simply adding cream directly?

A

The roux creates a stable thickening base that prevents the sauce from separating when cheese and half‑and‑half are added. It also adds a subtle nutty flavor that enhances the overall richness.

technical
Q

Can I make seafood lasagna rolls ahead of time and how should I store them before baking?

A

Yes. Assemble the rolls, cover the baking dish tightly with plastic wrap, and refrigerate up to 24 hours. For longer storage, freeze the assembled rolls on a tray, then transfer to a freezer bag; bake from frozen, adding extra baking time.

technical
Q

What texture and appearance should I look for when the seafood lasagna rolls are done cooking?

A

The cheese on top should be melted, lightly golden, and bubbling. The rolls should be firm to the touch but still moist inside, and the seafood should be opaque and tender.

technical
Q

What does the YouTube channel Tiff Spice Be Rite! specialize in?

A

The YouTube channel Tiff Spice Be Rite! specializes in vibrant, flavor‑forward home cooking videos that blend classic comfort foods with bold spice profiles, often featuring seafood, poultry, and creative twists on familiar dishes.

channel
Q

How does the YouTube channel Tiff Spice Be Rite!'s approach to Italian‑American cooking differ from other cooking channels?

A

Tiff Spice Be Rite! focuses on integrating global spice blends—like Cajun seasoning—into traditional Italian‑American recipes, offering a unique flavor fusion while keeping techniques accessible for home cooks.

channel

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