Chicken Alfredo with Fettuccine

Chicken Alfredo with Fettuccine is a medium Italian-American recipe that serves 4. 750 calories per serving. Recipe by Mr. Make It Happen on YouTube.

Prep: 15 min | Cook: 35 min | Total: 1 hr 5 min

Cost: $14.30 total, $3.57 per serving

Ingredients

  • 2 large Chicken Breast (skinless, boneless)
  • 1 tablespoon Olive Oil (extra-virgin)
  • 4 tablespoons Butter (unsalted, divided)
  • 1 teaspoon Lemon Pepper Seasoning (or freshly grated lemon zest + black pepper)
  • to taste Salt
  • 12 ounces Fettuccine Pasta (dry)
  • 1 medium Shallot (finely minced)
  • 3 cloves Garlic (minced)
  • 1 cup Heavy Cream (35% fat)
  • 1 teaspoon Cajun Seasoning
  • 1 cup Parmesan Cheese (freshly grated)
  • 2 tablespoons Fresh Parsley (chopped, optional garnish)

Instructions

  1. Season Chicken

    Pat chicken breasts dry, then season both sides with lemon pepper seasoning, salt, and pepper.

    Time: PT5M

  2. Sear Chicken

    Heat skillet over medium‑high heat, add olive oil, and place chicken breasts skin‑side down. Sear 4‑5 minutes until golden brown.

    Time: PT8M

    Temperature: medium‑high

  3. Baste and Finish in Oven

    Add 2 Tbsp butter to the skillet, tilt pan and baste chicken for 1 minute. Transfer skillet to a pre‑heated oven at 375°F and bake 12‑15 minutes, or until internal temperature reaches 165°F.

    Time: PT15M

    Temperature: 375°F

  4. Cook Pasta

    Bring a large pot of salted water to a boil, add fettuccine, and cook 8‑10 minutes until al dente. Drain, reserving ½ cup pasta water.

    Time: PT10M

    Temperature: boiling

  5. Prepare Sauce

    In a saucepan melt 2 Tbsp butter over medium heat. Add minced shallot and sauté 2 minutes until translucent, then add garlic and cook 30 seconds. Pour in heavy cream, stir, then add Cajun seasoning, lemon pepper, and grated Parmesan. Simmer 4‑5 minutes, stirring, until sauce thickens. If too thick, add reserved pasta water.

    Time: PT8M

    Temperature: medium

  6. Combine Pasta and Sauce

    Add cooked fettuccine to the sauce, toss to coat evenly. Adjust seasoning with salt or extra pepper if needed.

    Time: PT3M

  7. Slice Chicken and Plate

    Remove chicken from oven, let rest 3 minutes, then slice diagonally. Place a mound of sauced pasta on each plate, top with sliced chicken, drizzle extra sauce, and garnish with parsley and extra Parmesan.

    Time: PT5M

Nutrition Facts

Calories
750
Protein
45 g
Carbohydrates
60 g
Fat
35 g
Fiber
2 g

Dietary info: High‑protein, Contains gluten, Contains dairy

Allergens: Dairy, Gluten

Last updated: April 7, 2026

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Chicken Alfredo with Fettuccine

Recipe by Mr. Make It Happen

A creamy, comforting Chicken Alfredo made from scratch with seared chicken breasts, homemade Alfredo sauce, and fettuccine pasta. No jarred sauce needed—just butter, cream, Parmesan, and a touch of lemon pepper and Cajun seasoning for depth.

MediumItalian-AmericanServes 4

Shop all ingredients on Amazon in one click • Printable PDF with shopping checklist

Source Video
18m
Prep
36m
Cook
10m
Cleanup
1h 4m
Total

Cost Breakdown

$14.30
Total cost
$3.57
Per serving

Critical Success Points

  • Searing chicken to develop a golden crust
  • Finishing chicken in the oven to reach safe internal temperature
  • Thickening the Alfredo sauce without curdling

Safety Warnings

  • Handle hot skillet and oven tray with oven mitts to avoid burns.
  • Ensure chicken reaches 165°F internal temperature.
  • Be careful when adding hot cream to prevent splatter.

Frequently Asked Questions

Everything you need to know about this recipe

Q

What is the cultural significance and history of Chicken Alfredo in Italian-American cuisine?

A

Chicken Alfredo evolved from the classic Italian fettuccine Alfredo, which was created in early 20th‑century Rome. Italian immigrants in the United States added protein like chicken to make the dish heartier, turning it into a beloved comfort food for family dinners and gatherings.

cultural
Q

What are the traditional regional variations of Chicken Alfredo in Italian-American cuisine?

A

In the U.S., variations often include adding broccoli, peas, or shrimp. Some families use a blend of Parmesan and Romano cheeses, while others incorporate a pinch of nutmeg or white pepper for subtle flavor twists.

cultural
Q

What is the authentic traditional way Chicken Alfredo is served in Italian-American households?

A

It is typically served hot over a mound of al dente fettuccine, topped with sliced chicken, a generous drizzle of extra sauce, freshly grated Parmesan, and a sprinkle of chopped parsley for color and freshness.

cultural
Q

What occasions or celebrations is Chicken Alfredo traditionally associated with in Italian-American culture?

A

Chicken Alfredo is a go‑to dish for casual family dinners, weekend gatherings, and holiday meals like Christmas Eve or Thanksgiving when a comforting, crowd‑pleasing main is needed.

cultural
Q

How does Chicken Alfredo fit into the broader Italian-American cuisine tradition?

A

It exemplifies the Italian‑American tradition of taking a simple Italian pasta concept and enriching it with abundant dairy, butter, and protein, reflecting the American love for rich, indulgent comfort foods.

cultural
Q

What are the most common mistakes to avoid when making Chicken Alfredo at home?

A

Common errors include overcooking the chicken, letting the sauce boil too vigorously which causes curdling, and adding too much cream which makes the sauce watery. Follow the sear‑then‑oven method and keep the sauce on medium heat.

technical
Q

Why does this Chicken Alfredo recipe use butter basting instead of extra oil for the chicken?

A

Basting with butter adds a rich, nutty flavor and helps keep the chicken moist while it finishes in the oven, creating a more luxurious mouthfeel that complements the creamy Alfredo sauce.

technical
Q

Can I make Chicken Alfredo ahead of time and how should I store it?

A

Yes. Cook the chicken and sauce separately, store them in airtight containers in the refrigerator for up to 3 days, and reheat gently over low heat, adding a splash of pasta water if the sauce thickens too much.

technical
Q

What does the YouTube channel Mr. Make It Happen specialize in?

A

The YouTube channel Mr. Make It Happen specializes in straightforward, no‑nonsense home cooking tutorials that focus on building dishes from scratch, avoiding pre‑made shortcuts, and delivering bold flavor with simple techniques.

channel
Q

How does the YouTube channel Mr. Make It Happen's approach to comfort food differ from other cooking channels?

A

Mr. Make It Happen emphasizes real‑time cooking, minimal equipment, and a philosophy of “no jarred sauce” to ensure every flavor is fresh. This contrasts with many channels that rely on packaged ingredients for speed.

channel

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