Cajun Shrimp Lasagna

Cajun Shrimp Lasagna is a medium Cajun recipe that serves 6. 460 calories per serving. Recipe by The Stay At Home Chef on YouTube.

Prep: 30 min | Cook: 1 hr 21 min | Total: 2 hrs 11 min

Cost: $20.72 total, $3.45 per serving

Ingredients

  • 1 tablespoon Olive Oil (extra virgin, for sautéing)
  • 1 medium Onion (diced very small)
  • 1 medium Bell Pepper (any color, diced very small)
  • 2 stalks Celery (diced very small)
  • 6 cloves Garlic (crushed)
  • 4 tablespoons Cajun Seasoning (store‑bought or homemade (recipe in video description))
  • 28 oz Crushed Tomatoes (canned, no added herbs)
  • 6 oz Tomato Paste (canned)
  • 2 teaspoons Granulated Sugar (balances acidity)
  • 4 oz Mozzarella Cheese (shredded)
  • 4 oz Sharp Cheddar Cheese (shredded)
  • 4 oz Monterey Jack Cheese (shredded)
  • 15 oz Whole Milk Ricotta (full‑fat for richness)
  • 2 large Eggs (room temperature)
  • 1 cup Parmesan Cheese (freshly grated)
  • 1 lb Shrimp (peeled, deveined, tails removed, chopped)
  • 9 pieces No‑Boil Lasagna Noodles (standard 9‑inch sheets, overlap slightly when layering)
  • 1 sheet Aluminum Foil (for covering during baking)

Instructions

  1. Sauté the Cajun Trinity

    Heat the saucepan over medium‑high heat, add 1 tbsp olive oil, then add the diced onion, bell pepper, and celery. Cook, stirring occasionally, until softened, about 5 minutes.

    Time: PT5M

    Temperature: medium‑high

  2. Toast Garlic and Cajun Spice

    Add the crushed garlic cloves and 2 tbsp Cajun seasoning to the pan. Stir constantly for 1 minute until fragrant.

    Time: PT1M

    Temperature: medium‑high

  3. Build the Tomato Sauce

    Stir in 28 oz crushed tomatoes, 6 oz tomato paste, and 2 tsp sugar. Reduce heat to low and let the sauce simmer, uncovered, for 15 minutes, stirring occasionally.

    Time: PT15M

    Temperature: low

  4. Combine Shredded Cheeses

    In a mixing bowl, combine the shredded mozzarella, sharp cheddar, and Monterey Jack. Mix gently; set aside.

    Time: PT5M

  5. Prepare Ricotta Mixture

    In another bowl, whisk together the whole‑milk ricotta, 2 large eggs, 1 cup grated Parmesan, 1 tbsp Cajun seasoning, and a handful of the shredded cheese mixture. Mix until smooth.

    Time: PT5M

  6. Season the Shrimp

    Place the chopped shrimp in a bowl, sprinkle with 1 tbsp Cajun seasoning, and toss to coat evenly.

    Time: PT5M

  7. Preheat Oven & Grease Pan

    Preheat the oven to 375°F. Lightly grease the 9×13‑inch baking dish with a little olive oil to prevent sticking.

    Time: PT10M

    Temperature: 375°F

  8. First Layer Assembly

    Spread a thin layer of sauce on the bottom of the dish. Lay a single layer of no‑boil noodles, overlapping slightly. Spoon half of the ricotta mixture over the noodles, then sprinkle half of the seasoned shrimp, and finally top with one‑third of the shredded cheese mixture.

    Time: PT10M

  9. Second Layer Assembly

    Repeat: add another layer of noodles, the remaining sauce, the rest of the ricotta mixture, the remaining shrimp, and another third of the shredded cheese mixture.

    Time: PT5M

  10. Final Layer & Cover

    Place the final layer of noodles, top with the remaining sauce, and finish with the last third of shredded cheese. Loosely cover the dish with aluminum foil.

    Time: PT5M

  11. Bake Covered

    Bake in the preheated oven for 40 minutes.

    Time: PT40M

    Temperature: 375°F

  12. Bake Uncovered

    Remove the foil and continue baking for an additional 20 minutes, or until the cheese on top is golden‑brown and bubbly.

    Time: PT20M

    Temperature: 375°F

  13. Rest & Serve

    Allow the lasagna to rest for 10 minutes before cutting. This helps the layers set and makes serving easier.

    Time: PT10M

Nutrition Facts

Calories
460
Protein
32 g
Carbohydrates
38 g
Fat
22 g
Fiber
4 g

Dietary info: High‑protein, Contains seafood, Contains gluten

Allergens: Dairy, Shellfish, Eggs, Gluten

Last updated: April 7, 2026

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Cajun Shrimp Lasagna

Recipe by The Stay At Home Chef

A spicy, creamy lasagna that layers no‑boil noodles with a rich Cajun‑spiced tomato sauce, three cheeses, ricotta‑egg mixture, and succulent shrimp. Perfect for a bold dinner that feels restaurant‑quality but is easy enough for a home kitchen.

MediumCajunServes 6

Shop all ingredients on Amazon in one click • Printable PDF with shopping checklist

Source Video
46m
Prep
1h 30m
Cook
16m
Cleanup
2h 32m
Total

Cost Breakdown

$20.72
Total cost
$3.45
Per serving

Critical Success Points

  • Sauté the vegetables until softened but not browned.
  • Toast garlic and Cajun seasoning briefly to release aromatics.
  • Simmer the tomato sauce for at least 15 minutes to develop flavor and thicken.
  • Ensure noodles are fully coated with sauce during assembly to prevent dryness.
  • Cover with foil for the first 40 minutes of baking, then uncover for a golden top.

Safety Warnings

  • Hot oil can cause burns – handle the saucepan with care.
  • Raw shrimp must be cooked to an internal temperature of 145°F (63°C).
  • Use oven mitts when handling the hot baking dish and foil.

Frequently Asked Questions

Everything you need to know about this recipe

Q

What is the cultural significance and history of Cajun Shrimp Lasagna in Louisiana cuisine?

A

Cajun cuisine blends French, African, and Native American influences, emphasizing bold spices and seafood. While lasagna is Italian, Cajun chefs have adapted it by layering spicy shrimp and a robust Cajun tomato sauce, creating a fusion that showcases Louisiana’s love for both comfort food and seafood.

cultural
Q

What are the traditional regional variations of Cajun Shrimp Lasagna in Southern United States cooking?

A

In coastal Louisiana, cooks may add Andouille sausage or use a roux‑based sauce instead of plain tomatoes. Some versions substitute crab or crawfish for shrimp, and others incorporate okra or bell peppers for extra texture, reflecting local seafood availability.

cultural
Q

How is authentic Cajun Shrimp Lasagna traditionally served in Louisiana households?

A

It is typically served hot from the oven, cut into squares, and accompanied by a simple green salad, crusty French bread, and a cold glass of iced tea or a light lager. A sprinkle of fresh parsley or green onions adds a bright finish.

cultural
Q

What occasions or celebrations is Cajun Shrimp Lasagna traditionally associated with in Cajun culture?

A

The dish is popular for family gatherings, Mardi Mardi celebrations, and casual dinner parties because it combines festive spice with a crowd‑pleasing baked format that can feed a group easily.

cultural
Q

What makes Cajun Shrimp Lasagna special or unique in Cajun cuisine?

A

It fuses the comforting, layered structure of Italian lasagna with the bold, smoky heat of Cajun seasoning and the sweet briny flavor of shrimp, creating a one‑dish meal that highlights the region’s love for spice and seafood.

cultural
Q

What are the most common mistakes to avoid when making Cajun Shrimp Lasagna?

A

Common errors include under‑seasoning the shrimp, using a sauce that’s too watery, and not covering the lasagna long enough, which can leave the noodles dry. Also, over‑cooking the shrimp before baking makes them rubbery.

technical
Q

Why does this Cajun Shrimp Lasagna recipe use no‑boil lasagna noodles instead of regular noodles?

A

No‑boil noodles absorb moisture from the sauce during baking, eliminating the need to pre‑cook them and ensuring the layers stay tender. This also reduces overall prep time and keeps the dish less soggy.

technical
Q

Can I make Cajun Shrimp Lasagna ahead of time and how should I store it?

A

Yes. Assemble the lasagna, cover tightly with foil, and refrigerate for up to 24 hours before baking. For longer storage, freeze the assembled, unbaked lasagna; bake from frozen, adding 10‑15 minutes to the bake time.

technical
Q

What texture and appearance should I look for when the Cajun Shrimp Lasagna is done cooking?

A

The top cheese should be golden‑brown and bubbling, and the noodles should be tender with no visible dry edges. A gentle jiggle in the center indicates the interior is hot and set.

technical
Q

What does the YouTube channel The Stay At Home Chef specialize in?

A

The Stay At Home Chef focuses on restaurant‑quality, approachable recipes that home cooks can recreate with everyday ingredients, covering a wide range of cuisines and cooking techniques.

channel
Q

How does the YouTube channel The Stay At Home Chef's approach to Cajun cooking differ from other Cajun cooking channels?

A

The Stay At Home Chef blends classic Cajun flavors with familiar comfort‑food formats like lasagna, emphasizing step‑by‑step guidance, ingredient flexibility, and practical kitchen hacks, whereas many Cajun channels stick to traditional dishes such as gumbo or jambalaya.

channel

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